Azetidin-2-Ones Based on Pyrimidine-Sulfonamide Clubbed Derivative

The presence of >C=N- group is of great importance by considering the fact that it can be transformed into various heterocyclic ring compounds. The availability of the presence and significant biological properties of the members known so far prompted the authors to extend moieties like 2-azetidinones. Various Schiff bases Schiff based of 4-amino-N-(4-(2,4-dichlorophenyl)-6-(6-methylnaphthalen-2-yl)pyrimidin-2-yl)benzenesulfonamide (6a-h) mentioned in chapter-2 on heterocyclization reaction with chloroacetyl chloride yield the biologically active 2-azetidinones (β-lactams).