The role of glutathione in male infertility

Male infertility proves to be a psychological distress for the married couples. Numerous research studies have attempted to determine the causes of male infertility with the objective of developing therapeutic approaches to effectively improve various semen parameters. The presented intervention is a quantitative approach that categorically assesses the therapeutic advantage of oral GSH (glutathione) administration on various semen parameters including sperm concentration, morphology, and motility in infertile males. The study hypothesis presumes the positive/linear correlation of the selected sperm parameters with orally administered glutathione. The findings recorded at 0 weeks, 3 months, and 6 months interval revealed a significant p-value (between 0.01 to 0.03 for sperm motility, morphology, and concentration.